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jimson weed seeds effects

Koevoets, P. F. and van Harten, P. N. [Thorn apple poisoning]. Ned.Tijdschr.Geneeskd. 5-3-1997;141(18):888-889. View abstract.

Mikolich, J. R., Paulson, G. W., and Cross, C. J. Acute anticholinergic syndrome due to Jimson seed ingestion. Clinical and laboratory observation in six cases. Ann.Intern.Med. 1975;83(3):321-325. View abstract.

Rissech, Payret M. and Garcia, Tornel S. [Datura stramonium poisoning]. Med.Clin.(Barc.) 11-25-1979;73(9):397. View abstract.

SLIDESHOW

Oberndorfer, S., Grisold, W., Hinterholzer, G., and Rosner, M. Coma with focal neurological signs caused by Datura stramonium intoxication in a young man. J Neurol.Neurosurg.Psychiatry 2002;73(4):458-459. View abstract.

Thabet, H., Brahmi, N., Amamou, M., Ben Salah, N., Hedhili, A., and Yacoub, M. Datura stramonium poisonings in humans. Vet.Hum.Toxicol. 1999;41(5):320-321. View abstract.

Betz, P., Janzen, J., Roider, G., and Penning, R. [Psychopathologic manifestations of oral administration of endemic nightshade plants]. Arch.Kriminol. 1991;188(5-6):175-182. View abstract.

Burnham TH, ed. Drug Facts and Comparisons, Updated Monthly. Facts and Comparisons, St. Louis, MO.

Andreola, B., Piovan, A., Da Dalt, L., Filippini, R., and Cappelletti, E. Unilateral mydriasis due to Angel’s trumpet. Clin.Toxicol.(Phila) 2008;46(4):329-331. View abstract.

Grandjean, E. M., de Moreloose, P., and Zwahlen, A. [Acute atropinic syndrome caused by abuse of anti-asthmatic cigarettes (Datura stramonium)]. Schweiz.Med.Wochenschr. 8-16-1980;110(33):1186-1190. View abstract.

Insufficient Evidence for

Constipation: Jimson weed might cause constipation.

Pregnancy and breast-feeding: Jimson weed is UNSAFE for both mother and child when taken by mouth or inhaled.

Burnham TH, ed. Drug Facts and Comparisons, Updated Monthly. Facts and Comparisons, St. Louis, MO.

Jimson weed (Datura stramonium, a member of the Belladonna alkyloid family) is a plant growing naturally in West Virginia and has been used as a home remedy since colonial times. Due to its easy availability and strong anticholinergic properties, teens are using Jimson weed as a drug. Plant parts can be brewed as a tea or chewed, and seed pods, commonly known as “pods” or “thorn apples,” can be eaten. Side effects from ingesting jimson weed include tachycardia, dry mouth, dilated pupils, blurred vision, hallucinations, confusion, combative behavior, and difficulty urinating. Severe toxicity has been associated with coma and seizures, although death is rare. Treatment consists of activated charcoal and gastric lavage. Esmolol or other beta-blocker may be indicated to reduce severe sinus tachycardia. Seizures, severe hypertension, severe hallucinations, and life-threatening arrhythmias are indicators for the use of the anticholinesterase inhibitor, Physostigmine. This article reviews the cases of nine teenagers who were treated in hospitals in the Kanawha Valley after ingesting jimson weed. We hope this article will help alert primary care physicians about the abuse of jimson weed and inform health officials about the need to educate teens about the dangers of this plant.