CBD Oil

CBDISTILLERY

Buy CBD Oil Online

+PlusCBD is a top selling brand for natural CBD oil plus THC. CBD gummies, CBD capsules, CBD drops, balm & more! Find the Perfect CBD product for you. Last month, a U.S. Food and Drug Administration advisory panel unanimously recommended approval of the CBD medication Epidiolex to treat two rare forms of childhood epilepsy. CBD oil has skyrocketed in popularity thanks to its purported calming effects. Here are nine ways studies suggest CBD oil could benefit your health.

CBD Oil

CBD OIL RESERVE COLLECTION 1OZ DARK CHOCOLATE MINT

CBD with THC Formula

CBD OIL RESERVE COLLECTION 1OZ DARK CHOCOLATE MINT

CBD with THC Formula

CBD SOFTGEL CAPSULES 15MG 30CT

Extra Strength Formula

CBD SOFTGEL CAPSULES 15MG 30CT

Extra Strength Formula

CBD OIL 750MG 1.86OZ PEPPERMINT

Extra Strength Formula

CBD OIL 750MG 1.86OZ PEPPERMINT

Extra Strength Formula

Maximum Strength Formula

Maximum Strength Formula

Sleep

We’ve all been there. Lying awake. unable to will our body to sleep. CBD can help regulate sleep and wake cycles, so you can rest and recharge.

I am a Believer

Verified Reviewer Dec 22, 2021

I am great believer in the PlusCBD products. I’ve been a customer for 3+ years. It helps reduce joint pain and contributes to a more positive, energetic state of mind.

CBD BALM 100MG 1.3OZ

Extra Strength Formula

CBD BALM 100MG 1.3OZ

Extra Strength Formula

CBD PAIN RELIEF PENETRATING CREAM 2oz

CBD PAIN RELIEF PENETRATING CREAM 2oz

CBD ROLL-ON 500MG 1.13OZ

Extra Strength Formula

CBD ROLL-ON 500MG 1.13OZ

Extra Strength Formula

CBD RELIEF SOFTGEL CAPSULES 30MG CBD/CBDA 30CT

Wellness Blends Formula

CBD RELIEF SOFTGEL CAPSULES 30MG CBD/CBDA 30CT

Wellness Blends Formula

CBD TRAVEL SIZE BALM 45MG 0.42OZ

Extra Strength Formula

CBD TRAVEL SIZE BALM 45MG 0.42OZ

Extra Strength Formula

  • CBD Balm for Soreness
  • CBD Hemp for Soreness

Soreness

Work hard. Play hard. CBD oil, according to developing research, can help alleviate the occasional discomfort and soreness that comes from a life well lived.

Calming effect with this product.

Verified Reviewer Jan 4, 2022

Calming effect with this product. Ease of ordering and prompt delivery.

CBD CALM GUMMIES 10MG 30CT

Wellness Blends Formula

CBD CALM GUMMIES 10MG 30CT

Wellness Blends Formula

CBD OIL RESERVE COLLECTION 1OZ LEMON GINGER

CBD with THC Formula

CBD OIL RESERVE COLLECTION 1OZ LEMON GINGER

CBD with THC Formula

CBD SOFTGEL CAPSULES 15MG 90CT

Extra Strength Formula

CBD SOFTGEL CAPSULES 15MG 90CT

Extra Strength Formula

CBD SOFTGEL CAPSULES 50MG 60CT

Maximum Strength Formula

CBD SOFTGEL CAPSULES 50MG 60CT

Maximum Strength Formula

CBD GUMMIES 10MG 60 CT CHERRY MANGO

Extra Strength Formula

CBD GUMMIES 10MG 60 CT CHERRY MANGO

Extra Strength Formula

  • CBD Gummies for Stress
  • CBD Oil for Stress

Stress

Life’s demands can dial up the stress. When things get hectic, we’ve got you covered. +PlusCBD products can help restore your balance and keep you calm, cool, and collected.

Common CBD Questions

CBD (cannabidiol) is one of over 100 cannabinoids found in the hemp plant. CBD oil works naturally with the body’s own endocannabinoid system (ECS) to promote wellness without getting you “high”. Researchers have demonstrated that CBD has multiple benefits throughout the body, making it a smart new addition to your wellness regimen.

The answer to this is always personal. We recommend initially that people take their CBD oil in the morning and the evening, but everyone’s rhythm is different. Some people find CBD activating and only take it in the morning, while others only take their CBD at night for more restful sleep.* Many others take it multiple times per day as needed. So while twice a day is often the right answer, you might find your own rhythm for when to enjoy your CBD oil each day.

Yes, if it comes from hemp! Thanks to the signing of the 2018 Farm Bill, the era of hemp prohibition is over. Hemp can be cultivated, processed into products like CBD supplements, and sold across the United States if the THC level is at or below 0.3%. However, some states have additional laws regarding CBD product sales and use, so it is important to check local laws and regulations. Marijuana products, even those with high levels of CBD, are still federally illegal in this country.

Probably! That is because everyone has an endocannabinoid system (ECS) that helps your body maintain homeostasis. When you are feeling out of sorts, cannabinoid compounds can interact with your ECS to help restore balance back to your body, and that is why such a wide array of people report feeling better and healthier after taking CBD.* We most often see people reach for our products to support their stress response, sleep cycles, and soreness and recovery, or to simply promote better wellness.*

+PlusCBD products are made from nutrient-rich hemp, are non-intoxicating, and the first to be self-affirmed Generally Recognized as Safe (GRAS). All our CBD products are third party tested and fully traceable from seed to shelf, so you can be assured you are getting only the highest quality hemp CBD oil.

CBD and other cannabinoids are derived from hemp plants. A variety of cannabis that’s very low in THC and high in CBD, hemp has been used by humans since before the dawn of agriculture. We source our hemp from both domestic U.S. and European partner farms, allowing us to create a wide choice of effective CBD product formulations. Once our hemp is harvested, we use clean, safe CO2 to extract the hemp’s cannabinoid and nutrient packed oil and process it into our daily use supplements.

See also  Mayim Bialik Uly CBD Gummies

CBD Oil: All the Rage, But Is It Safe & Effective?

MONDAY, May 7, 2018 (HealthDay News) — Cannabidiol (CBD) oil has become the hot new product in states that have legalized medical marijuana.

The non-intoxicating marijuana extract is being credited with helping treat a host of medical problems — everything from epileptic seizures to anxiety to inflammation to sleeplessness.

But experts say the evidence is scant for most of these touted benefits.

Worse, CBD is being produced without any regulation, resulting in products that vary widely in quality, said Marcel Bonn-Miller, an adjunct assistant professor of psychology in psychiatry at the University of Pennsylvania School of Medicine.

“It really is the Wild West,” Bonn-Miller said. “Joe Bob who starts up a CBD company could say whatever the hell he wants on a label and sell it to people.”

Cannabidiol is extracted from the flowers and buds of marijuana or hemp plants. It does not produce intoxication; marijuana’s “high” is caused by the chemical tetrahydrocannabinol (THC).

CBD oil is legal in 30 states where medicinal and/or recreational marijuana is legal, according to Governing magazine.

Seventeen additional states have CBD-specific laws on the books, according to Prevention magazine. Those are Alabama, Georgia, Indiana, Iowa, Kentucky, Mississippi, Missouri, North Carolina, Oklahoma, South Carolina, South Dakota, Tennessee, Texas, Utah, Virginia, Wisconsin and Wyoming.

Strong Evidence for Treating Epilepsy

Only one purported use for cannabidiol, to treat epilepsy, has significant scientific evidence supporting it.

Last month, a U.S. Food and Drug Administration advisory panel unanimously recommended approval of the CBD medication Epidiolex to treat two rare forms of childhood epilepsy.

“That’s really the only area where the evidence has risen to the point where the FDA has said this is acceptable to approve a new drug,” said Timothy Welty, chair of the department of clinical sciences at Drake University’s College of Pharmacy and Health Sciences, in Des Moines, Iowa.

For the rest of CBD’s potential uses, there is simply too little evidence to make a firm conclusion.

For example, some human clinical trials suggest that CBD could be effective in treating symptoms of anxiety, particularly social anxiety, Bonn-Miller said.

This is the potential use for CBD with the most evidence after usefulness in epilepsy, but “there’s a decent gap between those two,” he said.

“There have been clinical trials in adults, but a lot smaller than the epilepsy studies that have been done in kids,” Bonn-Miller said.

CBD’s usefulness as an anti-inflammatory medication is the next most promising, but those results come mostly from animal studies, experts said.

Most Other Uses Largely Unproven

The rest of the potential uses — as an antipsychotic, antidepressant or sleep aid “have all been studied in animals, with only one or two examples of studies in humans,” Bonn-Miller said.

And Welty said the studies that have featured humans for these other CBD uses have either been case reports or studies that did not compare results against a control group that did not use the oil.

“There’s no control, so it’s basically how do you know if we’re dealing with the true effect of the drug or just simply a placebo effect because somebody thinks they’ve been given a drug that will be beneficial?” Welty said.

There also are concerns about both the quality of CBD oil being produced and its potential side effects, the experts added.

Lack of Regulation Also Concerning

Because of the legally murky nature of marijuana, the FDA has not stepped in to regulate products like CBD oil, Bonn-Miller said. States are struggling to put regulations in place, but they don’t have the deep pockets of the federal government.

Meanwhile, a 2017 study led by Bonn-Miller found that nearly 7 of 10 CBD products didn’t contain the amount of marijuana extract promised on the label.

Nearly 43 percent of the products contained too little CBD, while about 26 percent contained too much, Bonn-Miller said.

“CBD is kind of a tricky drug because it’s not very well absorbed orally,” Welty explained. “Less than 20 percent of the drug is absorbed orally. If it isn’t made in the right way, you may not be getting much drug into your systemic circulation.”

Worse, about 1 in 5 CBD products contained the intoxicating pot chemical THC, Bonn-Miller and his colleagues found.

“That’s a problem because THC can increase anxiety. It can actually make seizures worse. Those are the sorts of things you need to be careful about,” Bonn-Miller said.

“If I were a consumer, purchasing it for myself or my kid, I would want to test it so that I knew what it actually had in it, because I couldn’t trust what was on the label,” Bonn-Miller concluded.

Potential Interactions With Other Meds

Studies on CBD also have raised concerns about possible interactions with other drugs.

For example, epilepsy studies found that “there were very clearly increases in the blood levels of some other anti-epileptic drugs when people were on CBD,” Welty said.

This could mean that people taking anti-epilepsy drugs alongside CBD will need to adjust their dosage downward to avoid side effects, Welty noted.

There also is some indication that CBD might harm the liver. About 10 percent of people taking CBD in studies had increases in liver enzymes, which would indicate possible liver damage, Welty said.

See also  Trazodone And CBD Oil For Sleep

“About 2 to 3 percent of individuals taking CBD actually had to discontinue because their liver enzymes went so high it was of concern to the people running the study,” he said.

Welty recommends that people interested in CBD seek out a doctor who has read up on the extract and its potential uses.

“My bottom-line advice is people really need to be under the care of a health care provider who understands CBD. They need to be monitored and managed by that individual, and not just go out and buy CBD thinking it’s going to be the answer,” Welty said.

Show Sources

SOURCES: Marcel Bonn-Miller, Ph.D., adjunct assistant professor, psychology in psychiatry, University of Pennsylvania School of Medicine, Philadelphia; Timothy Welty, Pharm.D., chair, department of clinical sciences, College of Pharmacy and Health Sciences, Drake University, Des Moines, Iowa

CBD Oil: 9 Science-Backed Benefits

Dr. Bindiya Gandhi is an integrative medicine physician with expertise in functional and holistic medicine based in Atlanta, Georgia.

Commissions we earn from partner links on this page do not affect our opinions or evaluations. Our editorial content is based on thorough research and guidance from the Forbes Health Advisory Board.

Cannabidiol, or CBD, is a chemical compound found in the cannabis sativa plant. When applied topically or consumed through smoke inhalation or edible consumption, CBD interacts with neuroreceptors in your endocannabinoid system, which sends signals between your cells to help regulate your movement, mood, homeostasis and immune system.

You May Also Be Interested In CBD Oils From Our Featured Partner

Isolate CBD Oil

On Medterra’s Website

500mg,1000mg, 3000mg, 6000mg

True Full Spectrum™ CBD Oil

On Medterra’s Website

750mg,1500mg, 3000mg, 6000mg

Chocolate Mint, Citrus

Ultra Broad Spectrum™ CBD Oil

On Medterra’s Website

Citrus, Strawberry Mint, Unflavored

Immune Boost CBD Oil

On Medterra’s Website

On Medterra’s Website

(Note: Product details and price are accurate as of publication and are subject to change.)

CBD is often extracted from the cannabis sativa plant in oil form and mixed with an inert carrier oil like hemp seed oil for consumption. In fact, of the 60% of U.S. adults who report having used CBD before, 55% of them use CBD oils and tinctures specifically, according to a recent Forbes Health survey of 2,000 U.S. adults conducted by OnePoll.

CBD research is growing, too. Here are nine ways studies suggest CBD oil could benefit your health.

1. Offset Anxiety and Depression

CBD’s ability to calm is perhaps its most popular effect and the reason its use is so widespread. A 2017 study in the Brazilian Journal of Psychiatry tested the anxiety levels of 57 men in a simulated public speaking test. Some received a placebo while others received either 150 milligrams, 300 milligrams or 600 milligrams of CBD before their speeches. Those who received 300 milligrams of CBD experienced significantly reduced anxiety during the test compared to those who received the placebo. Interestingly, participants who received either 150 or 600 milligrams of CBD experienced more anxiety during the test than the 300 milligrams group.

Meanwhile, at least one study in mice revealed CBD had effects similar to the antidepressant imipramine. Human trials are needed, though, to confirm whether CBD can induce this same antidepressant reaction in our bodies.

2. Treat Select Epilepsy Syndromes

In some instances, CBD can be used to treat epileptic seizures.

In 2018, the Food and Drug Administration (FDA) approved the use of CBD under the brand name Epidiolex to treat seizures resulting from Lennox-Gastaut syndrome and Dravet syndrome—two rare forms of epilepsy—in patients at least 2 years old.

Three well-vetted studies provide the basis of support for the FDA’s decision. In these trials, 516 patients with Lennox-Gastaut syndrome or Dravet syndrome received either Epidiolex or a placebo. Epidiolex, when taken along with other prescribed medications, decreased the frequency of participants’ seizures compared to the placebo.

3. Reduce PTSD Symptoms

In a small 2018 study in the Journal of Alternative and Complementary Medicine, 11 people with post-traumatic stress disorder (PTSD) received CBD along with routine psychiatric care for eight weeks in an outpatient psychiatric clinic. Ten of the 11 experienced a decrease in their PTSD symptoms. CBD was generally well tolerated, the researchers write.

Margaret Rajnic, a doctor of nursing practice experienced in medical cannabis and CBD, emphasizes the importance of using therapy in tandem with any type of cannabis or CBD for PTSD. “There is an amount of therapy that is needed for PTSD,” she says. “But CBD will give you that little bit of decreased anxiety.”

Four other human trials from 2012 to 2016 suggest CBD reduces PTSD symptoms, although some include THC, or tetrahydrocannabinol, the main mind-altering element in cannabis. When THC and CBD work together, they create what’s called an “entourage effect,” complementing each other’s benefits and potency. For example, taking the same dose of THC and CBD together tempers the “high” from THC, while just a little THC paired with more CBD enhances the effects of the CBD.

4. Treat Opioid Addiction

Some studies—both preclinical animal and human clinical trials—suggest CBD could be used to help treat people who are dependent on opioids.

In one such study, researchers administered CBD to people with heroin use disorder. Over the course of a week, CBD significantly reduced heroin users’ cue-induced cravings, withdrawal anxiety, resting heart rate and salivary cortisol levels. No serious adverse effects were found.

See also  Does CBD Oil Make You Hungry

Other studies find CBD helpful in reducing various psychiatric and medical symptoms like anxiety, insomnia and pain in patients with substance use disorders, indicating that CBD may be an effective treatment for opioid addiction. However, further studies are necessary.

5. Alleviate ALS Symptoms

Amyotrophic lateral sclerosis (ALS) is a disease that causes nerve cells in the brain and spinal cord to deteriorate, resulting in loss of muscle control that worsens over time. It’s not yet understood exactly why ALS occurs, although it can be hereditary in some cases. There’s no known cure, and there are only two FDA-approved medications to help treat ALS symptoms.

Research suggests people with ALS can benefit from the entourage effect created by the combination of THC and CBD, similar to people with PTSD. In a 2019 study, patients received a combination of THC and CBD in varying doses depending on their needs and preferences. Those with mild, moderate or severe spasticity (muscle tightness and stiffness) due to ALS reported high levels of satisfaction with the treatment, and those with moderate to severe spasticity reported higher satisfaction rates than those with mild spasticity.

6. Relieve Unmanageable Pain

In 2005, Canada approved the use of Sativex, an oromucosal (absorbed in the lining of the mouth) spray with equal proportions of THC and CBD, for the treatment of multiple sclerosis-related central neuropathic pain. In 2007, Canada approved the medicine’s use again for cancer pain that proved unresponsive to other medications.

Meanwhile, continued studies in the U.S. indicate CBD is effective in treating chronic, non-cancer pain. In one 2020 study, researchers administered CBD topically to a group of patients with symptomatic peripheral neuropathy (a result of brain nerve and spinal cord nerve damage) while another group with the same condition received a placebo. Results showed a significant reduction in intense, sharp pains and cold, itchy sensations in those who used the topical CBD compared to those who used the placebo. No participants reported adverse side effects.

When introduced topically, CBD oil doesn’t affect the systemic issue as it might if it were introduced directly into the bloodstream. Instead, topical CBD is more localized and treats pain in a certain area. Since it’s more direct, it may have a more pronounced effect.

7. Ease Diabetic Complications

For starters, tests on human cells found that CBD helps reduce the effects of high glucose levels on other cells in the body, which typically precedes the development of diabetes and various complications. Researchers concluded that with further studies, CBD could have significant benefits when used in patients with diabetes, diabetic complications and plaque buildup in artery walls.

In another small study, 13 patients with type 2 diabetes who weren’t on insulin treatment were given both CBD and a placebo (in lieu of insulin). Researchers found CBD decreased their levels of resistin (which causes resistance to insulin, the protein that regulates sugar levels) and increased their levels of glucose-dependent insulinotropic peptide (a hormone that ensures a sufficient release of insulin from digested food) compared to their baselines before they started the test. These results suggest CBD could be a natural treatment for diabetes by helping the body regulate insulin-related hormone levels.

8. Protect Against Neurological Disease

Preclinical and clinical studies show that CBD has antioxidant and anti-inflammatory properties. Researchers deduce these characteristics can provide significant neuroprotection, or protection against numerous pathological disorders.

Several preclinical studies suggest CBD can produce beneficial effects against Parkinson’s disease, Alzheimer’s disease and multiple sclerosis. Huntington’s disease and cerebral ischemia were also tested, although significant positive results were not recorded. Further clinical studies are needed to confirm CBD’s benefits when used as a treatment for these disorders.

9. Inhibit Arthritis Symptoms

Arthritis involves the deterioration of the tissues in and around your joints. There are several types of arthritis, and symptoms include pain, stiffness and loss of motion. Arthritis treatment usually targets pain relief and improved joint function.

A 2006 study found that Sativex—a CBD-based botanical drug approved in the United Kingdom in 2010—promoted statistically significant improvements in quality of sleep, pain during movement and pain at rest in patients with rheumatoid arthritis when compared to a placebo. It was the first controlled trial of Sativex as a treatment for rheumatoid arthritis, involving 58 patients. CBD was found to have a pain-relieving effect, as well as an ability to suppress disease activity.

In 2018, in a study of more localized treatment, researchers administered a synthetic CBD gel in either 250-milligram or 500-milligram doses daily or a placebo to patients with knee pain due to osteoarthritis. Patients also stopped taking any other anti-inflammatory medications or painkillers, with the exception of acetaminophen, before and during the study period.

The results were interesting, although not entirely conclusive. On one hand, those treated with CBD did not experience much change in pain when compared with placebo patients. On the other hand, there were statistically significant differences between the group receiving the 250-milligram dose and the placebo group when measuring the average weekly improvement of their worst pain levels and their WOMAC (Western Ontario and McMaster Universities Arthritis Index) physical function rating. Additionally, men seemed to benefit from CBD more significantly than women in this test.

How useful was this post?

Click on a star to rate it!

Average rating 3 / 5. Vote count: 1

No votes so far! Be the first to rate this post.